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Self-infection. — Steffeck (11) has examined tlie vaginal discharges or secretions in twenty-nine women — pregnant — who had not been subjected Dilantin 1 G to digital ex- amination, and Dilantin 130 Mg found the Staphylococcus pyogenes albus in nine, Staphylococcus pyogenes aureus in three, and Streptococcus pyogenes in one. Walthard reports tiie result of the examination of the secretion from the vaginae of one hundred pregnant women who had not been subjected to digital examination; streptococci were found twenty-seven times in cultures. These were not virulent, but they became virulent when placed in a suitable medium; and with a reduced power of resist- ance, such as we have in the puerperium, they are en- abled to invade the tissues. Kronig, in his report of nearly five hundred cases in 1894, found the vaginal secretions to be acid, the inten- sity of the reaction varying in the different cases. In no cases did he Dilantin 400 Mg find the Streptococcus pyogenes or the pyogenic staphylococcus. His conclusions were that the vaginal secretions of untouched pregnant Dilantin 125 women contained nothing septic, and were therefore aseptic. Kronig and Menge have made experiments proving that bacteria, including the Streptococcus pyogenes and the Dilantin 500 Mg pyogenic staphylococcus, could be introduced, even in large quantities, into the vagina of a pregnant or non- pregnant woman, and would disappear in a short time, say from six to thirty-six hours. In only one case did the vagina become affected, and that was the result of an accidental wound of the vagina. In all the other eases they began to disappear almost immediately after their introduction. What the bactericidal properties of the vagina were due to they could not say; they were supposed to be due to the acid secretion; but this would not apply to the cervix uteri, from which they disappeared just as rapid- ly, as this, of course, is alkaline. Doberlin, in the bacteriological examination of one hundred and ninety-five pregnant women, in 55.3 found acid normal vaginal secretions. According to his defini- tion, the only bacteria were the acid-producing bacilli. In 44.6 per cent, he found what he called a pathological secretion, feebly acid, neutral, or alkaline, containing various bacilli and cocci. Dilantin 50 Mg In ten per cent, of the latter he found the Streptococcus pyogenes, which proved pathogenic in one lialf of Dilantin 350 Mg the cases inoculated. Again, in his work on vaginal secretions, he explains the appar- ently different results of different observers. He de- scribes the normal vaginal secretion as a whitish ma- terial, of the consistence of clotted milk, with a strongly acid reaction; microscopically, it contains a long ba- cillus, a few epithelial cells, and, occasionally, a few yeast cells. The pathological secretion, on the other hand, has a yellowish or a yellowish-green color; is of a creamy consistence; its reaction is weakly acid, neutral, or alkaline; it contains large quantities of micro-organ- isms — bacilli, as well as cocci — and considerable quanti- ties Dilantin Xr of leucocytes and epithelial cells. His conclu- sions were Dilantin 200 Mg that the normal vaginal secretion presents absolutely no possibility for self-infection, but rather appears to be germicidal in its action, Dilantin 330 Mg as small quanti- ties of pyogenic organisms, when introduced in a vagina with a normal secretion, were soon destroyed. His ex- planation of the divergent results of different investiga- tors is, that those who obtained negative results hap- pened to experiment with normal vaginal Cheap Dilantin secretions, while the others met with both. Dr. J. Whitridge Williams, of the Johns Hopkins University, substantiates the results of Doberlin in a Dilantin Pharmacology report of the examination of fifteen women. This is also confirmed by Steffech, Dilantin 250 Mg Winters, and others; the general conclusion being that auto-infection is possi- ble, but very improbable. Germicides (13). — Before going on to the treat- ment I should Too Much Dilantin like to refer to the relative values of the different germicides. The statements made by the dif- ferent bacteriologists have been so conflicting, and so many fallacies shown, that Crookshank says that there is no wider field for research than the determining of the real effect of disinfectants and antiseptics. Koch"s investigations resulted in favor of the mercurial salts. Herron cultivated ordinary septic bacteria in albumi- nous filtrates, and concluded that the value Dilantin Ex of mercuric chloride Dilantin 230 Mg was much Dilantin 600 Mg overrated. It is precij^itatcd by albumins, but, as Lister has shown, the precipitate of albuminate of mercury is dissolved when there is an ex- cess of albumin present. Geppert and Behring recognized later on that the methods employed for testing the efficacy of corro- sive sublimate were unreliable. They found, for in- stance, that it could not be removed from silk threads by washing, and, consequently, the time for its action could not be definitely determined, and that in order to do this it was necessary to dip the threads in am- monium sulphide after treatment with the corrosive sublimate. Crookshank confirms the results of Geppert and Behring, and has made a series of experiments to test the value respectively Dilantin 150 Mg of carbolic acid and corrosive sub- limate in antiseptic surgery. He discarded the method adopted heretofore, of washing the Dilantin 30 Mg thread after it was taken from the mercurial solution in alcohol, as falla-

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